Reloaded my first box of .22-250 today. Used the Lee Ultimate 4-die set, full length resize (new brass). First time using Lee's 'factory crimp' die; like it. This was my first time reloading a bottle-neck case since ~1980. Not quite the same process as for straight wall handgun cartridges. The powder kind of hides in the .22-250 case; you have to look close for it when you're in the bullet seating step. And, I had to relearn how to guide the bullet into the seating die. When the job is done, the cartridges are pretty though.